2025-26 NFL Conference Winner Odds

Before reaching the Super Bowl, NFL teams must first win their respective conferences, allowing bettors to add more futures to their season-long portfolios. Placing wagers in this market can help bettors hedge their Super Bowl futures or add even more profit if they happen to place the right bets for both markets.

With the 2025-26 season underway, we’ll take a look at the odds of winning both the AFC and NFC across all legal sportsbooks in Louisiana.

2025-26 To Win the AFC - Best Odds Right Now

Odds as of September 10, 2025

* = the same odds are offered by multiple sportsbooks.

2025-26 Odds to Win the AFC - Top10 Contenders

Odds as of September 10, 2025

Current Favorites

Buffalo Bills: Josh Allen took home the first MVP award of his career during the 2024-25 season, but he was still unable to beat Patrick Mahomes in the AFC Championship. Their ability to get over the hump remains the biggest question, but in just one game during the 2025-26 season, the Bills certainly look like Super Bowl contenders once again, as they mounted a big 4th-quarter comeback over the Ravens.

Baltimore Ravens: The Ravens have failed to reach the Super Bowl in the Lamar Jackson era, and despite going 12-5 during the 2024-25 season, they were unable to advance past the AFC Championship game. Especially after acquiring Derrick Henry, the Ravens have continued to be a dominant regular-season team, but whether they can reach the promised land with Lamar Jackson remains to be determined.

Kansas City Chiefs: The Chiefs have won the AFC five times since 2019. While they could not complete the Super Bowl three-peat, they opened as the favorite to win their fourth consecutive AFC title. While the Chiefs will still have Patrick Mahomes under center and a few more key players on defense, they certainly fell short of addressing a few key areas this offseason, and in Week One, the Chiefs suffered their first loss, as they fell to the Chargers.

Previous AFC Winners & Odds

2025-26 To Win the NFC - Current Best Odds

Odds as of September 10, 2025

* = the same odds are offered by multiple sportsbooks.

2025-26 Odds to Win the NFC - Top10 Contenders

Odds as of September 10, 2025

Current Favorites

Philadelphia Eagles: For the second time since 2018, the Philadelphia Eagles were able to hoist the Lombardi Trophy. Behind their otherworldly defense and offense led by Saquon Barkley, the Eagles entered this season as the team to beat in the NFC. During their Week One matchup, the Eagles took care of business against the Cowboys. However, in that win, some concerns arose about their secondary and play-calling now that Kellen Moore is gone.

Green Bay Packers: It is essentially unheard of to acquire a franchise-altering player one week before the season starts, but the Packers have become the exception. In shocking news, the Packers were able to trade for Micah Parsons from the Dallas Cowboys, which instantly boosted their odds for division, conference, and Super Bowl titles. Green Bay finished 5th in the league last season in points allowed per game and average yards allowed per play, so Parsons will only bolster an already strong defense. It didn't take him long to make an impact either, as Green Bay opened the year with a dominant win over the Lions.

Washington Commanders: The Commanders shocked a lot of football fans by reaching the NFC Championship game last season, but moving forward, it will no longer be a shock to reach that point. With Jayden Daniels under center, the Commanders' offense has a good chance of being on an elite level, so as long as their defense can be as dominant as they were in Week One against the Giants, then Washington could be in for another long postseason run.

Past NFC Winners & Odds

AFC number 1 seed betting odds - TOP5 favorites

NFC number 1 seed odds - TOP5 favorites

Using DVOA and EPA to Time Conference Futures Bets

What a bettor values and analyzes for their futures bets is the difference between a quality winning bet and a losing bet. Sure, injuries and roster construction hold weight, but advanced metrics can often get overlooked by casual bettors, which causes them to miss out on value and hidden contenders that the market is overlooking. 

Two key advanced metrics that sharp bettors like to examine are EPA (Expected Points Added) and DVOA (Defense-adjusted Value Over Average). Since DVOA looks at how a team performs in comparison to the league average and adjusts for opponent strength, teams with average records at the start of the year that have a top-10 DVOA could be a team to look out for come the playoffs. 

One of the most important things that these stats offer is context, as they go beyond the box score to show efficiency on both sides of the ball. The 2024 season provided a strong glimpse of how valuable these stats can be. Through the first eight weeks of the season, the Washington Commanders' offense led the league in EPA per play, yet in Week 8, they were still (+1400) to win the NFC. 

While they didn’t win the NFC, they still provided sharp bettors who took advantage of the market not adjusting to a valuable hedging opportunity.

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