2025-26 NFL Conference Winner Odds

Before reaching the Super Bowl, NFL teams must first win their respective conferences, allowing bettors to add more futures to their season-long portfolios. Placing wagers in this market can help bettors hedge their Super Bowl futures or add even more profit if they happen to place the right bets for both markets.

With the 2025-26 season entering Week 15, we’ll take a look at the odds of winning both the AFC and NFC across all legal sportsbooks in Louisiana.

2025-26 To Win the AFC - Best Odds Right Now

Odds as of December 10, 2025

* = the same odds are offered by multiple sportsbooks.

2025-26 Odds to Win the AFC - Top10 Contenders

Odds as of December 10, 2025

Current Favorites

New England Patriots: Ever since they beat the Bills early in the season, the New England Patriots have not looked back. With Drake Maye playing at an MVP-caliber level in just his second NFL season, the Patriots have found success a lot quicker than many expected, as their 11-2 record has them sitting in first place in the AFC East. Behind Maye on offense, the Patriots rank 11th in success rate, while new head coach Mike Vrabel has helped guide the defense to be ranked 9th in EPA per play, per RBSDM.

Buffalo Bills: The Bills have been all over the odds board this season. Every time it seems like they are garnering momentum, they suffer a surprising loss, and on the flip side, when it looks like they are trending down, Josh Allen saves the day and gets them back in the win column. The past five weeks have been a perfect example of that, as they have lost games to the Dolphins and Texans, only to turn around and beat the Buccaneers, Steelers, and Bengals. With their defense ranked 13th in success rate and Josh Allen leading the offense, the biggest thing missing is consistency.

Denver Broncos: In year two of the Bo Nix era, the Broncos look well on their way to ending the Chiefs' longstanding streak of winning the AFC West. After a win over the Raiders, the Broncos have won ten straight games, giving them an 11-2 record. While Nix has been solid in his sophomore season, Denver's true calling card is their defense, which ranks 7th in EPA per play and 2nd in success rate (RBSDM).

Previous AFC Winners & Odds

2025-26 To Win the NFC - Current Best Odds

Odds as of December 10, 2025

* = the same odds are offered by multiple sportsbooks.

2025-26 Odds to Win the NFC - Top10 Contenders

Odds as of December 10, 2025

Current Favorites

Los Angeles Rams: Aside from three losses by one possession, the LA Rams have played at a nearly flawless level. With Matthew Stafford continuing to play at an MVP-caliber pace and their defense ranking third in the league in EPA per play, the Rams have asserted their dominance on both sides of the ball. After a blowout win over the Cardinals, the Rams hold first place in the NFC West and the second-best point differential in the league (+152).

Seattle Seahawks: The Seahawks have been a competitive team over the past few seasons, and especially since Mike Macdonald took over. However, their ceiling, especially on offense, has been raised by having Sam Darnold under center. With Darnold proving last season in Minnesota was no fluke and the Seahawks ranking 4th in success rate, Seattle has the best point differential in the league (+161) to go with their 10-3 record.

Green Bay Packers: Over the past four weeks, the Packers have started to look like the team many expected them to be before the season began. With a 28-21 win over the Bears to give them control of first place in the NFC North, the Packers are in the midst of a four-game winning streak. Behind Jordan Love, the Green Bay offense has been humming during that span, ranking 2nd in EPA per play since Week Eight (RBSDM).

Past NFC Winners & Odds

AFC number 1 seed betting odds - TOP5 favorites

NFC number 1 seed odds - TOP5 favorites

Using DVOA and EPA to Time Conference Futures Bets

What a bettor values and analyzes for their futures bets is the difference between a quality winning bet and a losing bet. Sure, injuries and roster construction hold weight, but advanced metrics can often get overlooked by casual bettors, which causes them to miss out on value and hidden contenders that the market is overlooking. 

Two key advanced metrics that sharp bettors like to examine are EPA (Expected Points Added) and DVOA (Defense-adjusted Value Over Average). Since DVOA looks at how a team performs in comparison to the league average and adjusts for opponent strength, teams with average records at the start of the year that have a top-10 DVOA could be a team to look out for come the playoffs. 

One of the most important things that these stats offer is context, as they go beyond the box score to show efficiency on both sides of the ball. The 2024 season provided a strong indication of the value these statistics can bring. Through the first eight weeks of the season, the Washington Commanders' offense led the league in EPA per play, yet in Week 8, they were still (+1400) to win the NFC. 

While they didn’t win the NFC, they still provided sharp bettors who took advantage of the market not adjusting to a valuable hedging opportunity.

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